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Approved for Combination Use with solifenacin succinate*
*Marketed in the US as VESIcare®
Approved for Combination Use
For adults with overactive bladder symptoms of urgency, frequency and leakage, Myrbetriq® (mirabegron) is FDA-approved for use in combination with solifenacin succinate*. Ask your doctor if this combination treatment may be right for you.
*Marketed in the US as VESIcare®
Call for Savings: 1-855-984-6304
†Subject to eligibility. Restrictions may apply.

What is MYRBETRIQ?

MYRBETRIQ is a prescription medicine for adults that can be used alone or with solifenacin succinate to treat the following symptoms due to a condition called overactive bladder:

  • Urge urinary incontinence: a strong need to urinate with leaking or wetting accidents
  • Urgency: a strong need to urinate right away
  • Frequency: urinating often

It is not known if MYRBETRIQ, when used alone or with solifenacin succinate, is safe and effective in children.

How should I take MYRBETRIQ?

  • If your doctor prescribes MYRBETRIQ and solifenacin succinate together, you should take 1 MYRBETRIQ tablet and 1 solifenacin tablet at the same time, 1 time a day.
  • You should take MYRBETRIQ with water and swallow the tablet whole.
  • Do not chew, break, or crush the tablet.
  • You can take MYRBETRIQ with or without food.
  • You can take MYRBETRIQ and solifenacin succinate together with or without food.

The most common side effects of MYRBETRIQ, when used with solifenacin succinate, include:

  • dry mouth
  • urinary tract infection
  • constipation
  • fast heartbeat

USE OF MYRBETRIQ

Myrbetriq® (mirabegron) is a prescription medicine for adults that can be used alone or with solifenacin succinate to treat overactive bladder (OAB) with symptoms of urgency, frequency and leakage.

IMPORTANT SAFETY INFORMATION FOR MYRBETRIQ

Myrbetriq is not for everyone. Do not take Myrbetriq if you have an allergy to mirabegron or any ingredients in Myrbetriq. Myrbetriq may cause your blood pressure to increase or make your blood pressure worse if you have a history of high blood pressure. It is recommended that your doctor check your blood pressure while you are taking Myrbetriq. Myrbetriq may increase your chances of not being able to empty your bladder. Tell your doctor right away if you have trouble emptying your bladder or you have a weak urine stream.

Myrbetriq may cause allergic reactions that may be serious. If you experience swelling of the face, lips, throat or tongue, with or without difficulty breathing, stop taking Myrbetriq and tell your doctor right away.

Tell your doctor about all the medicines you take including medications for overactive bladder or other medicines such as thioridazine (Mellaril™ and Mellaril-S™), flecainide (Tambocor®), propafenone (Rythmol®), digoxin (Lanoxin®), or solifenacin succinate (VESIcare®). Myrbetriq may affect the way other medicines work, and other medicines may affect how Myrbetriq works.

Before taking Myrbetriq, tell your doctor if you have liver or kidney problems. The most common side effects of Myrbetriq include increased blood pressure, common cold symptoms (nasopharyngitis), dry mouth, flu symptoms, urinary tract infection, back pain, dizziness, joint pain, headache, constipation, sinus irritation, and inflammation of the bladder (cystitis).

The most common side effects of MYRBETRIQ, when used with solifenacin succinate, include dry mouth, urinary tract infection, constipation, and fast heartbeat.

For further information, please talk to your healthcare professional and see accompanying Patient Product Information and complete Prescribing Information for Myrbetriq® (mirabegron).

USE OF VESICARE

VESIcare® (solifenacin succinate) is for overactive bladder with symptoms of urgency, frequency, and leakage.

IMPORTANT SAFETY INFORMATION FOR VESICARE

VESIcare is not for everyone. If you have certain stomach or glaucoma problems, or trouble emptying your bladder, do not take VESIcare. VESIcare may cause allergic reactions that may be serious. If you experience swelling of the face, lips, throat, or tongue, stop taking VESIcare and get emergency help. Tell your doctor right away if you have severe abdominal pain, or become constipated for three or more days. VESIcare may cause blurred vision, so use caution while driving or doing unsafe tasks. Common side effects are dry mouth, constipation, and indigestion.

For further information, please talk to your healthcare professional and see accompanying Patient Product Information and complete Prescribing Information for VESIcare® (solifenacin succinate).

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Myrbetriq® and VESIcare® are registered trademarks of Astellas Pharma Inc. All other trademarks or registered trademarks are the property of their respective owners.

Save up to $840 over one year! Subject to eligibility. Restrictions may apply.

Myrbetriq® (mirabegron) is a prescription medicine for 
adults used to treat overactive bladder (OAB) with symptoms of urgency, frequency and leakage.

Living With OAB Symptoms

In this section, you'll learn about:
  • OAB and who has it
  • What symptoms to look for
  • Lifestyle tips that can help

What is OAB?

About About 1 in 3 U.S. adults 40 years of age and older reported symptoms of OAB at least 'sometimes' U.S. adults 40 years of age and older reported symptoms of
OAB at least "sometimes."

OAB occurs when you cannot control your bladder contractions.

When these muscle contractions happen too often or cannot be controlled, you can get symptoms of OAB, which are urgency, frequency, and leakage.

If you have these symptoms, you're not alone. As many as 46 million Americans 40 years of age or older have reported symptoms of OAB. According to the American Urological Association, OAB:

  • occurs in both men and women
  • may affect your daily activities due to lack of bladder control
  • can cause embarrassment, leading some
    to just learn to cope with the condition

Rather than planning your daily activities around being close to bathrooms to avoid urine leaks and accidents, it may be time to have an honest talk with your healthcare professional (HCP). Lifestyle changes can help. And there are treatment options available.

How OAB Happens

A healthy bladder muscle expands as it fills with urine. Once it's
about half full, nerves in the bladder tell you it's time to urinate.

OAB interrupts the normal
storage of urine by causing the bladder muscle to suddenly contract before the bladder is full.

This can lead to frequent and sudden, strong urges to urinate, sometimes with leakage.

Think you are part of the 1 in 3 patients that are living with OAB symptoms? See how these patients managed their OAB.*

Penelope's Personal Story with Myrbetriqagment

Penelope leads an active lifestyle.
She hasn't let OAB stop her.

Jim's Personal Story with Myrbetriq

Jim's dog runs the house.
But Jim's OAB symptoms were running him.

*Your results may vary.

Symptoms of OAB

The symptoms of OAB can have you searching for a bathroom, anytime, anywhere. They can come over you suddenly, and they are hard to control. If you have some or all of the following symptoms, your HCP may prescribe an OAB treatment for you.

Urgency

Urgency is when you feel a strong need to urinate that is difficult to control; it may even be strong enough to cause urine leakage.

Frequency

Frequency means that you need to urinate too often; urinating more than seven times
during waking hours is one of the primary symptoms of OAB.

Leakage

Leakage is also known as “accidentally
urinating” after a sudden, uncontrollable
urge; those trying to cope with leakage
may wear absorbent products like pads in
case of wetting accidents.

Are you experiencing the symptoms of OAB?

Watch these videos to learn more about the signs and the effects.

OAB Doctor

OAB: What to Look For

National OAB educator and Nurse Practitioner Diane Newman, DNP, talks about the symptoms of OAB.

OAB Doctor

OAB: Know its Effects

Nurse Practitioner Newman discusses how OAB may affect daily activities.

Find a specialist to talk to about your OAB symptoms
Powered by VITALS®

Lifestyle Tips

A prescription medicine is just one aspect of managing your OAB symptoms. If your HCP prescribes one, be sure to follow the prescription instructions exactly as written and ask what you can expect from the medication. You may also benefit from making certain lifestyle changes, such as the ones shown below.

  • Too Much Spice Won’t Play Nice

    It's time to rethink that extra dab of hot sauce. Spicy foods—such as tomato products, chili and horseradish—can irritate the bladder and worsen the symptoms of OAB. Also, instead of dousing food with hot spices, focus on increasing flavor with seasonal herbs and garlic.

    Always talk to your HCP before starting any diet or exercise program.

  • Another Cup and It Could Act Up

    You may enjoy the occasional cup of joe, but cutting down on caffeine could result in fewer bathroom trips. The acid and caffeine in coffee, including decaf, can be problematic.

    When it comes to herbal teas, chamomile and peppermint are generally a safe bet. If you have to live life one cup at a time, try hot milk with a touch of vanilla.

  • Think Before You Drink

    As a rule, alcohol and your bladder don’t mix well. Alcohol can irritate your bladder and drinking less may reduce your symptoms.

  • Watching Your Weight may
    Improve Your State

    If you’re carrying around extra pounds,
    you could be putting unnecessary pressure on
    your bladder. Low-impact activities like walking, Pilates and yoga could help you lose weight and help ease OAB symptoms. But always be sure to talk to your HCP before starting any weight loss or exercise program.

  • Sip Sensibly, Live More Comfortably

    If you are dealing with symptoms of OAB,
    you may be tempted to reduce your fluid intake
    as much as possible. However, this can irritate your bladder. Instead, try to manage your fluid intake throughout the day.
    Check with your doctor to see what the
    right amount is for you.

  • One Option Lies in Exercise

    Kegel exercises use muscle contractions to strengthen the pelvic floor—which can help with control and urge suppression.

    Another simple exercise you can do is
    bladder training, such as delayed voiding (urinating), which is essentially holding off going to the bathroom until you gradually increase the time between voids. Always check with your doctor when starting a new exercise program.

  • Squeeze Out the Citrus

    Citrus fruits such as oranges, limes, lemons
    and grapefruit can irritate the bladder. If you enjoy fruit juice, consider switching to less acidic
    beverages like pear juice or apple juice.

  • Stop! Drop That Pop!

    Sodas often contain either caffeine or citric acid, both of which may irritate your bladder. And, while diet sodas may not contain sugar, their artificial sweeteners aren’t the healthiest option, either.

    A pitcher of ice-cold water with a few slices of watermelon could serve as a refreshing, and bladder-friendly alternative.

Start the Conversation with Your Doctor

Take the OAB Symptoms Quiz

Talking with Your Doctor

If you are experiencing symptoms of OAB, talking with your doctor about them should be your first step.
Here is a tool that will help you get started and make the most of your discussion. Using this tool is really simple!

Get Started Now!

1. How many times do you urinate during the day?
2. Do you have to rush to the toilet to urinate?
3. Does urine leak before you can get to the toilet?
Please complete the survey.

Sign Up for the Momentum Program

The Momentum Program is designed to help those taking Myrbetriq start strong and stay
on track with tips and tools delivered right to
their inbox or mailbox.

Sign up today
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Use of Myrbetriq

Myrbetriq® (mirabegron) is a prescription medicine for adults used to treat overactive bladder (OAB) with symptoms of urgency, frequency and leakage.

Important Safety Information

Myrbetriq is not for everyone. Do not take Myrbetriq if you have an allergy to mirabegron or any ingredients in Myrbetriq. Myrbetriq may cause your blood pressure to increase or make your blood pressure worse if you have a history of high blood pressure. It is recommended that your doctor check your blood pressure while you are taking Myrbetriq. Myrbetriq may increase your chances of not being able to empty your bladder. Tell your doctor right away if you have trouble emptying your bladder or you have a weak urine stream.

Myrbetriq may cause allergic reactions that may be serious. If you experience swelling of the face, lips, throat or tongue, with or without difficulty breathing, stop taking Myrbetriq and tell your doctor right away.

Tell your doctor about all the medicines you take including medications for overactive bladder or other medicines such as thioridazine (Mellaril™ and Mellaril-S™), flecainide (Tambocor®), propafenone (Rythmol®), digoxin (Lanoxin®) or solifenacin succinate (VESIcare®). Myrbetriq may affect the way other medicines work, and other medicines may affect how Myrbetriq works.

Before taking Myrbetriq, tell your doctor if you have liver or kidney problems. The most common side effects of Myrbetriq include increased blood pressure, common cold symptoms (nasopharyngitis), dry mouth, flu symptoms, urinary tract infection, back pain, dizziness, joint pain, headache, constipation, sinus irritation, and inflammation of the bladder (cystitis).

For further information, please talk to your healthcare professional and see accompanying Patient Product Information and complete Prescribing Information for Myrbetriq® (mirabegron).

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Myrbetriq® is a registered trademark of Astellas Pharma Inc. All other trademarks or registered trademarks are the property of their respective owners.

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Our Doctor Conversation Guide can help you start the overactive bladder conversation.

Show it to your doctor at your appointment!

Get your Doctor Conversation Guide